While psychotropic medications, such as antidepressants and mood stabilizers, are a huge asset to many struggling with various mental disorders, some people do not experience symptom relief .  This could result from many different factors, but one possibility is that the person simply does not have enough raw material (ie serotonin, dopamine, norephinephrine, etc.) for the medication to act upon.  This is due to the fact that psychotropic medications do not assist the body in making more neurotransmitters, rather they recycle or inhibit the actions of the neurotransmitters already present.  It is speculated that the long-term use of psychotropic medications may lead to depletion of certain neurotransmitter stores.  Specific amino acid based supplements, however, assist in the creation and synthesis of new neurotransmitters, making them a viable option for most and especially for those who are deriving little to no benefit from their psychotropic medication.